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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...

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Updated: Jun 3, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Sexual dysfunction in patients with Type 2 diabetes: A South Asian perspective.

Shahjada Selim1

  • 1Department of Endocrinology, Bangladesh Medical University, Bangladesh.

Best Practice & Research. Clinical Endocrinology & Metabolism
|June 1, 2026
PubMed
Summary

Sexual dysfunction is a common, yet underdiagnosed, issue in Type 2 Diabetes Mellitus patients, particularly in South Asia. Addressing this requires integrated, culturally sensitive care to improve patient quality of life.

Keywords:
South AsiaType 2 diabetes mellituscultural barriersdiabetic autonomic neuropathyendothelial dysfunctionerectile dysfunctionfemale sexual dysfunctionglycaemic controlhypogonadismphosphodiesterase-5 inhibitorssexual healthtestosterone deficiency

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Last Updated: Jun 3, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

  • Endocrinology
  • Sexual Medicine
  • Public Health

Background:

  • Sexual dysfunction (SD) is a prevalent complication of Type 2 Diabetes Mellitus (T2DM), with a high burden in South Asia.
  • SD significantly impacts quality of life, relationships, and well-being but is often overlooked in clinical practice due to sociocultural barriers and communication gaps.

Purpose of the Study:

  • To review current evidence on SD in T2DM, focusing on the South Asian context.
  • To identify regional and gender-specific data gaps.
  • To explore the impact of new glucose-lowering therapies on sexual health.

Main Methods:

  • Literature review consolidating evidence on SD in T2DM.
  • Emphasis on South Asian context and gender-specific manifestations.
  • Analysis of underlying mechanisms and management strategies.

Main Results:

  • Erectile dysfunction (ED) is common in men with T2DM, potentially preceding cardiovascular disease.
  • Women experience heterogeneous SD, including reduced desire, lubrication issues, and pain.
  • Complex mechanisms involve vascular, neurological, hormonal, psychological, and sociocultural factors.

Conclusions:

  • Comprehensive, culturally appropriate management is crucial for T2DM-related SD.
  • Integrated care involving glycaemic control, risk factor management, and psychosocial support is recommended.
  • Further research is needed on regional/gender-specific data and emerging therapies' effects on sexual health.