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Related Concept Videos

Electrodes: Overview01:17

Electrodes: Overview

Electrochemical measurements are conducted in an electrochemical cell composed of various components that control and measure the current and potential. One fundamental component is electrodes, conductive materials that enable electron transfer reactions at their surfaces.
There are two main types of electrodes in electrochemical cells. The first type, known as the working or indicator electrode, has a potential that is sensitive to the analyte's concentration and reacts to changes in the...
Voltammetry: Overview01:20

Voltammetry: Overview

Voltammetry is an electroanalytical technique in which the current flowing through an electrochemical cell is measured as a function of applied potential, typically under conditions of concentration polarization. The technique provides valuable information about redox-active species, and the current response is plotted as a voltammogram.
A voltammetric cell uses three electrodes: a working electrode, a reference electrode, and an auxiliary electrode. The redox reactions occur in the working...
Potentiometry: Types of Electrodes01:19

Potentiometry: Types of Electrodes

Reference electrodes serve as a stable reference point for potentiometric measurements, while indicator and working electrodes react to variations in the composition of a solution.
The Standard Hydrogen Electrode (SHE) is a widely used reference electrode that maintains zero potential across all temperatures. However, its need for a continuous hydrogen gas supply renders it impractical for everyday use.
An alternative to SHE is the Saturated Calomel Electrode (SCE). This electrode features an...
Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
Controlled-Current Coulometry: Overview01:27

Controlled-Current Coulometry: Overview

Controlled current coulometry, also known as amperostatic coulometry, is a technique used in electrochemical analysis to measure the quantity of a substance through the controlled passage of current. It involves the application of a constant current to an electrochemical cell containing the analyte of interest. As the current flows through the cell, the analyte undergoes a redox reaction at the electrode surface, resulting in a charge transfer. By monitoring the time required for a certain...
Coulometry: Overview01:00

Coulometry: Overview

Coulometry is one of the rapid, most accurate, and precise analytical techniques that determine the quantity of an analyte by measuring the electrical charge needed for its complete electrolysis without using any analytical standards. The total charge passed during electrolysis correlates with the analyte amount by Faraday's laws of electrolysis. For accurate coulometric measurements, a charge equal to Faraday's constant multiplied by the number of electrons involved in the relevant...

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Related Experiment Video

Updated: Jun 3, 2026

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing
06:55

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing

Published on: May 8, 2021

Hilab volt system for electrolyte measurement: a portable solution for point-of-care testing.

Ava Gevaerd1, Emmanuelle A Carneiro2, Jeferson L Gogola2

  • 1Research and Development Department, Hilab, Hilab Campus, Rua José A. Possebom, 800, Curitiba, 81270‑185, Parana, Brazil. ava.gevaerd@hilab.com.br.

Scientific Reports
|June 1, 2026
PubMed
Summary

The Hilab Volt system offers accurate point-of-care (POC) diagnostic testing for essential electrolytes. This electrochemical platform provides reliable results for decentralized clinical settings, improving accessibility.

Keywords:
Artificial InteligenceChlorideElectrochemistryElectrolytesIonized CalciumPoint-of-carePotassiumSodium

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A Simple, Low-cost, and Robust System to Measure the Volume of Hydrogen Evolved by Chemical Reactions with Aqueous Solutions
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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

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Last Updated: Jun 3, 2026

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A Simple, Low-cost, and Robust System to Measure the Volume of Hydrogen Evolved by Chemical Reactions with Aqueous Solutions
06:32

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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
05:35

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Clinical Diagnostics

Background:

  • Point-of-care (POC) diagnostic systems are crucial for rapid, reliable testing at the patient's location.
  • Decentralized testing requires user-friendly, accurate, and efficient diagnostic solutions.
  • Hilab developed a miniaturized electrochemical platform for integrated POCT.

Purpose of the Study:

  • To present and validate the analytical performance of the Hilab Volt system.
  • To assess the system's capability for detecting key electrolytes (K⁺, Na⁺, Ca²⁺, Cl⁻).
  • To demonstrate the suitability of the Hilab Volt for decentralized clinical testing.

Main Methods:

  • The Hilab Volt system, an electrochemical diagnostic platform with hardware, disposable sensors, and software, was utilized.
  • Analytical performance was validated by detecting essential electrolytes: potassium (K⁺), sodium (Na⁺), calcium (Ca²⁺), and chloride (Cl⁻).
  • Recovery ranges and correlation metrics using control samples were evaluated.

Main Results:

  • Recovery ranges for K⁺, Na⁺, Ca²⁺, and Cl⁻ were 84-112%, 94-101%, 80-125%, and 97-104%, respectively.
  • Satisfactory results were obtained for all sensors with control samples (r > 0.8, p > 0.8).
  • The system demonstrated reliable analytical performance for key electrolytes.

Conclusions:

  • The Hilab Volt system shows reliable analytical performance for key electrolytes, suitable for point-of-care use.
  • Its miniaturized design, ease of operation, and accurate detection support decentralized clinical testing.
  • The system offers a promising solution for rapid and accessible diagnostics in diverse care settings.