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Isolated Solar Angioedema: A Rare Case Successfully Treated With Dapsone.

Mary Grace H London1, Bret-Ashleigh Coleman1, Grace Herrick2

  • 1Medicine, Edward Via College of Osteopathic Medicine, Auburn, USA.

Cureus
|June 2, 2026
PubMed
Summary
This summary is machine-generated.

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Isolated solar angioedema (ISA) is a rare light-induced swelling. Dapsone showed promise in treating a patient with ISA resistant to standard therapies, suggesting its potential for managing this condition.

Area of Science:

  • Dermatology
  • Photodermatology
  • Immunology

Background:

  • Isolated solar angioedema (ISA) is an exceptionally rare photodermatosis.
  • Characterized by transient, painless angioedema triggered by UV or visible light, typically without urticaria or pruritus.
  • Diagnosis and effective management strategies for ISA remain unclear, with fewer than 10 cases documented.
Keywords:
angioedemadapsone therapyinflammationisolated solar angioedemaphotoimmunology

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