Related Experiment Video
Updated: Jun 3, 2026
07:10
Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
Published on: June 18, 2020
[Non-portal hypertension-related upper gastrointestinal bleeding]
Jérémie Albouys1, Pauline Pages1
1Service d'hépato-gastroentérologie et endoscopie digestive, CHU Dupuytren, Limoges, France.
La Revue Du Praticien
|June 2, 2026
Summary
Non-portal hypertension-related upper gastrointestinal bleeding (UGIB) is a common emergency. Advances in endoscopic techniques and devices improve management and outcomes for this serious condition.
Area of Science:
- Gastroenterology
- Endoscopy
- Emergency Medicine
Background:
- Non-portal hypertension-related upper gastrointestinal bleeding (UGIB) is a frequent gastroenterological emergency.
- It accounts for most UGIB cases in Western countries, with an incidence of 50-150 cases per 100,000 population annually.
- Mortality rates persist between 5-10% despite therapeutic advancements.
Purpose of the Study:
- To summarize the current understanding and management of non-portal hypertension-related UGIB.
- To highlight recent advancements in endoscopic therapies.
- To underscore the importance of prompt and structured patient management.
Main Methods:
- Review of current literature and clinical guidelines.
- Analysis of recent randomized trials on endoscopic techniques.
- Discussion of innovative endoscopic devices and their application.
Main Results:
- UGIB presents abruptly, often as hematemesis or melena, necessitating immediate resuscitation and endoscopic intervention.
- New endoscopic tools, including over-the-scope clips, hemostatic powders, and gels, have expanded therapeutic options.
- Research continues to refine endoscopy timing and compare the efficacy of different hemostatic techniques.
Conclusions:
- Effective management of non-portal hypertension-related UGIB relies on prompt resuscitation, timely endoscopy, and appropriate secondary prevention.
- Innovative endoscopic devices offer improved hemostatic capabilities.
- Ongoing research is crucial for optimizing treatment strategies and improving patient survival rates.
Keywords:
gastrointestinal bleeding
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