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Updated: Jun 4, 2026

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism
Published on: May 31, 2018
Considerations and best practices for respirometry
Andréa B Ball1, Linsey Stiles2, Ajit S Divakaruni1
1Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
None:
Oxygen consumption rate (OCR) measurements are now widely used to assess mitochondrial function and cellular metabolism. Here, we review the strengths and limitations of plate-based respirometry, propose unified reporting standards, and discuss how OCR measurements can be integrated with complementary assays to evaluate cellular energy demands and mitochondrial function.
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