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Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
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Updated: Jun 5, 2026

Measuring Diaphragm Thickness and Function Using Point-of-Care Ultrasound
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Published on: November 3, 2023

Assessment of Gallbladder Function in Type 2 Diabetes Using Three-Dimensional Ultrasound.

Tæraneh Jouleh1,2, Ingrid Kvåle Nordaas1, Spiros Kotopoulis1,2

  • 1Haukeland University Hospital, National Centre for Ultrasound in Gastroenterology, Norway, Bergen.

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [And] German Diabetes Association
|June 3, 2026
PubMed
Summary
This summary is machine-generated.

Diabetes duration impacts gallbladder volume in type 2 diabetes patients. Longer diabetes duration correlated with increased fasting and ejection gallbladder volumes, suggesting a link between diabetes progression and gallbladder changes.

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Area of Science:

  • Gastroenterology
  • Endocrinology
  • Diabetology

Background:

  • Gastrointestinal autonomic neuropathy is common in diabetes.
  • Gallbladder dysfunction can be a manifestation of this neuropathy.
  • Diabetes duration may influence gallbladder parameters.

Purpose of the Study:

  • To investigate the relationship between gallbladder volume and motility with diabetes duration.
  • To compare these parameters in individuals with type 2 diabetes versus non-diabetic controls.
  • To explore potential associations with autonomic neuropathy.

Main Methods:

  • Cross-sectional, observational case-control study design.
  • Inclusion of early type 2 diabetes, longstanding type 2 diabetes, and matched non-diabetic controls.
  • Gallbladder motility assessed via 3D ultrasound measurements of gallbladder volume changes post-meal.
  • Autonomic function evaluated using cardiovascular (Vagus) and sudomotor (Sudoscan) tests.

Main Results:

  • Sixty-one participants analyzed: 18 longstanding diabetes, 15 early diabetes, 28 controls.
  • Longstanding type 2 diabetes group showed significantly higher fasting gallbladder volume (p=0.020) and ejection volume (p=0.019) compared to controls.
  • No significant differences in other gallbladder motility parameters were found.
  • Autonomic neuropathy was present in only five participants.

Conclusions:

  • Diabetes duration is associated with specific gallbladder volume parameters.
  • Gallbladder motility was not significantly different between groups.
  • The study could not analyze associations between gallbladder motility and autonomic neuropathy due to limited cases.