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Updated: Jun 5, 2026
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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
MR Imaging/Ultrasound Fusion-Guided Biopsy and Primary Focal Therapy for Localized Prostate Cancer
Atsuko Fujihara1, Takumi Shiraishi1, Tsuyoshi Iwata2
1Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan.
Summary
Magnetic resonance imaging (MRI) and fusion technology enable precise targeting of prostate cancer. Focal therapy offers a promising alternative to whole-gland treatments, balancing cancer control with preserved function.
Area of Science:
- Urology
- Oncology
- Medical Imaging
Background:
- Advances in MRI allow visualization of clinically significant prostate cancer.
- Image-fusion technology enables precise targeting and biopsy of visualized lesions.
- Traditional whole-gland therapies risk side effects like incontinence and sexual dysfunction.
Purpose of the Study:
- To review MRI/ultrasound fusion-guided biopsy techniques.
- To discuss the current status and clinical implications of focal therapy for localized prostate cancer.
Main Methods:
- Review of advancements in MRI and image-fusion technology.
- Discussion of focal therapy principles and enabling technologies.
- Overview of MRI/ultrasound fusion-guided biopsy procedures.
Main Results:
- MRI and fusion-guided techniques facilitate accurate localization and sampling of prostate cancer.
- Focal therapy is technically feasible for localized prostate cancer.
- Focal therapy aims to preserve function while maintaining oncological control.
Conclusions:
- MRI/ultrasound fusion-guided biopsy is crucial for enabling focal therapy.
- Focal therapy represents a potential paradigm shift in localized prostate cancer treatment.
- This approach seeks to optimize outcomes by balancing cancer eradication and quality of life.
