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Updated: Jun 5, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[LYMPH NODE TUBERCULOSIS AFTER INTRAVESICAL BACILLUS CALMETTE-GUÉRIN THERAPY FOR BLADDER CARCINOMA IN SITU : A CASE
Tatsuya Sakai1, Toyofumi Abe1, Ryoya Mizuno1
1The Department of Urology, Sumitomo Hospital.
Abstract:
A 66-year-old female patient received a total of six intravesical Bacillus Calmette-Guérin instillations as treatment for bladder carcinoma in situ. Six months later, she visited our hospital with a complaint of abdominal pain. Computed tomography revealed enlarged para-aortic and left common iliac lymph nodes. A laparoscopic retroperitoneal biopsy of the left common iliac lymph node was performed. Acid-fast bacteria culture of the resected specimen and a multiplex polymerase chain reaction assay showed lymph node tuberculosis. There was no evidence of Bacillus Calmette-Guérin infection. We administered four anti-tuberculosis drugs. After one year of treatment, the enlarged lymph nodes showed regression. This reduction in lymph node size was sustained for four years.
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