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Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Related Experiment Video

Updated: Jun 5, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

Brain Stem Tumor in Early Gestation: Two Case Reports.

Taraneh Arbabzadeh¹, Parya Bamani Moghaddam¹, Nayyereh Rahmati²

¹Department of Obstetrics and Gynecology, Clinical Research Developmental Unit, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Iranian Journal of Medical Sciences

|June 4, 2026

Summary

Brainstem tumors in pregnancy are rare but dangerous. Overlapping symptoms with common pregnancy issues delay diagnosis, increasing maternal mortality risk. Early neurological evaluation is crucial for timely management.

Area of Science:

Neurology
Obstetrics and Gynecology
Oncology

Background:

Pontine and brainstem tumors are rare during pregnancy.
These tumors pose a high maternal mortality risk due to symptom overlap with common pregnancy conditions.

Keywords:

Brain neoplasms Brainstem neoplasms Pregnancy Pregnancy complications

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Diagnosis and management are often delayed and challenging.