Recurrent basosquamous carcinoma of the forearm, a case report

Basosquamous carcinoma (BSC) is a rare, aggressive skin cancer with histologic features of both basal and squamous cell carcinoma. This report describes an unusual case of rapidly growing and extensive BSC of the forearm in a 52-year-old male, a rare location for this cancer type. Despite surgical excision with near-complete margins and postoperative wound management using negative-pressure wound therapy (NPWT), the tumor recurred within eight weeks. The case raises concerns about the adequacy of margin control, the possible role of intraoperative tumor cell seeding, and the influence of NPWT and subsequent skin grafting on tumor recurrence. Following re-resection and radiotherapy, the patient achieved excellent functional outcomes, regaining good hand use and returning to competitive motorcycle racing. This case highlights key diagnostic, surgical, and postoperative challenges in managing aggressive BSC in an atypical location and suggests the need for further research into the safety of NPWT in oncologic surgery.