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nsP3-FXR co-condensation enables alphavirus replication and reveals a targetable alphavirus vulnerability

Yifan Xie1, Jie Cao1, Xinya Yang2

  • 1Life Sciences Institute, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Zhejiang University, Hangzhou 310058, Zhejiang, China; Department of Infectious Diseases, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou 310052, Zhejiang, China.

Cell Reports
|June 4, 2026
PubMed

Keywords:
CP: microbiologyRING-bait technologyalphavirusesantiviral strategybiomolecular condensationfragile X-related 1non-structural protein 3

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