Antenatal Corticosteroid Use in Twin Pregnancies: A Systematic Review and Meta-analysis

Carolina Alves Felippe1, Sinrraim Dos Santos Chaves Ruiz, Rebeca Ferreira de Souza

  • 1Universidade do Grande Rio José de Souza Herdy, Duque de Caxias, State University of Goiás-Itumbiara University Unit, Itumbiara, Goiás, Anhembi Morumbi University and Faculdade Santa Marcelina, São Paulo, Federal University of Campina Grande, Cajazeiras Campus, and Santa Casa de Misericórdia de Belo Horizonte, Belo Horizonte, Brazil; Autonomous University of Nuevo León, San Nicolás de los Garza, Mexico; Department of Gynecology and Obstetrics, University Hospital Ulm, Ulm, Germany; and Tel Aviv Sourasky Medical Center (Ichilov), Tel Aviv, Israel.

Summary

Antenatal corticosteroids (ACS) in twin pregnancies did not consistently improve neonatal outcomes, showing no reduction in mortality or respiratory distress syndrome (RDS). However, ACS exposure was linked to increased risks of hypoglycemia and NICU admission.

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