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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Early outcomes of emergency coronary artery bypass grafting based on institutional technique selection: a
1Department of Cardiovascular Surgery, Cardiology Institute, Istanbul University-Cerrahpaşa, Istanbul, Turkey. sdenizozsoy@hotmail.com.
Insights
Emergency coronary artery bypass grafting (CABG) is challenging. This study found both on-pump and off-pump CABG feasible using an algorithm, with outcomes reflecting patient factors, not technique superiority.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Cardiac Surgery
Background:
- Emergency coronary artery bypass grafting (CABG) in high-risk patients presents significant perioperative challenges.
- Surgical strategy is often dictated by clinical and anatomical factors rather than randomization.
- This study describes early outcomes of emergency CABG within a structured institutional technique selection framework.
Purpose of the Study:
- To describe early outcomes of emergency coronary artery bypass grafting (CABG).
- To evaluate the feasibility of on-pump versus off-pump CABG within a structured institutional technique selection framework.
- To assess the impact of an algorithm-guided approach on emergency CABG outcomes.
Main Methods:
- Retrospective cohort study of 59 consecutive patients undergoing emergency isolated CABG (2004-2007).
- Patients allocated to on-pump (n=39) or off-pump (n=20) CABG based on a predefined institutional algorithm.
- Outcomes presented descriptively; between-group comparisons interpreted considering selection bias.
Main Results:
- Substantial baseline and procedural differences observed between on-pump and off-pump groups, reflecting structured technique selection.
- On-pump CABG patients had more complex coronary anatomy and higher clinical acuity (including cardiogenic shock).
- In-hospital mortality was low and comparable (7.7% vs. 5.0%); findings are descriptive due to selection bias and small sample size.
Conclusions:
- Both on-pump and off-pump techniques are feasible for emergency CABG within a structured institutional framework.
- Observed early outcome differences likely reflect underlying patient characteristics, not intrinsic technique superiority.
- Algorithm-guided, individualized decision-making is crucial for emergency surgical revascularization.
Background:
Emergency coronary artery bypass grafting (CABG) in high-risk patients remains a major perioperative challenge, and surgical strategy is often determined by clinical and anatomical factors rather than randomization. This study aimed to describe early outcomes of emergency CABG within a structured institutional technique selection framework.
Methods:
This retrospective cohort study included 59 consecutive patients who underwent emergency isolated CABG between 2004 and 2007. Patients were allocated to on-pump (n = 39) or off-pump (n = 20) CABG according to a predefined institutional algorithm incorporating hemodynamic status, coronary anatomy, and comorbidities. Outcomes are presented descriptively, and between-group comparisons are interpreted in the context of inherent selection bias.
Results:
Substantial baseline and procedural differences were observed between groups, reflecting structured technique selection rather than random allocation. Patients undergoing on-pump CABG had more complex coronary anatomy and higher clinical acuity, including all four cardiogenic shock cases and 92.6% of triple-vessel grafting procedures. Longer operative time, increased inotropic support, and longer hospital stay were observed in the on-pump group; CK-MB levels at 1 h were lower in the off-pump group. In-hospital mortality was low and comparable (7.7% vs. 5.0%, p = 1.000). Given the marked selection bias and limited sample size, these findings should be considered descriptive rather than comparative.
Conclusion:
In this historical cohort of emergency CABG patients, both on-pump and off-pump techniques were feasible within a structured institutional selection framework. Observed differences in early outcomes likely reflect underlying patient characteristics rather than intrinsic superiority of either technique. These findings highlight the importance of individualized, algorithm-guided decision-making in emergency surgical revascularization.