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Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
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Published on: February 24, 2021

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Zhe Huang1, Yike Wang1,2, Matthew R Lowerison1

  • 1Department of Biomedical Engineering, Duke University, Durham, NC 27708 USA.

Biorxiv : the Preprint Server for Biology
|June 5, 2026
PubMed
Summary

This study establishes a new awake ultrasound imaging method for tracking neurovascular changes in mice over five months. The technique demonstrates high reproducibility and safety, offering a reliable tool for disease research.

Keywords:
Awake imagingFunctional ultrasoundLongitudinal imagingUltrasound localization microscopycerebrovascular imagingfunctional ultrasound localization microscopy

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