An Uncommon Unilateral Grade V Thumb Hypoplasia: A Cadaveric Case Report

Jenna Farnum1, Abby L Cummings1, Tristan D Packard1

  • 1Radiology, Division of Human Anatomy, College of Osteopathic Medicine, Michigan State University, East Lansing, USA.

Cureus
|June 5, 2026
PubMed

Thumb hypoplasia is a rare congenital anomaly often associated with other syndromic manifestations. This case study explores a unilateral grade V thumb hypoplasia of a 97-year-old male anatomical donor with a medical history of cerebral atherosclerosis, dementia, hypertension, benign prostatic hyperplasia, and a transient ischemic attack. A thorough dissection of the forearm and hand confirmed a suspected grade V thumb hypoplasia and atypical surrounding anatomy. This study contributes to the literature regarding thumb hypoplasia and discusses potential complications and areas of concern for related surgical procedures, congenital syndromes, or additional body-wide manifestations.