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Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy (NIRS) Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

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Connecting Rural Appalachia to Clinical Research: The Ambassadors for Community Health Research Program as a Model

Chloe Hatfield^1,2, Heather L Henderson^3,4, Bree Gustke⁴

¹West Virginia University School of Public Health, Morgantown, WV, USA.

Health Promotion Practice

|June 7, 2026

Summary

West Virginia

Keywords:

Appalachia clinical trials community engagement community-based interventions medical mistrust trust building

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Area of Science:

Community Health
Clinical Research
Health Equity

Background:

Rural Appalachia, particularly West Virginia, faces deep medical mistrust due to historical institutional betrayal and structural neglect.
This distrust creates significant barriers to engaging with healthcare and research institutions in underserved regions.
Previous trust-building initiatives have not fully addressed the unique challenges in Appalachia.

Purpose of the Study:

To introduce the Ambassadors for Community Health Research (ACHR) program, a novel initiative designed to address medical mistrust in West Virginia.
To outline the ACHR program's model for fostering collaboration between communities and clinical research teams.
To present a culturally authentic approach for enhancing trust and participation in health research in underserved areas.

Main Methods:

The Ambassadors for Community Health Research (ACHR) program trains community residents as liaisons for research teams.
Ambassadors receive year-long training in research ethics and health communication, focusing on relationship building.
The program facilitates two-way communication, exchanging community concerns, insights, and research evidence.

Main Results:

The ACHR program reframes research participation from a transactional event to a collaborative partnership.
This initiative aims to rebuild trust by embedding research within the community through trusted liaisons.
The model enhances the relevance, ethical conduct, and impact of clinical research in rural settings.

Conclusions:

The ACHR program offers a sustainable, culturally relevant model for rebuilding trust in health research within rural Appalachia.
This approach can serve as a roadmap for improving engagement and outcomes in underserved communities nationwide.
Fostering community-researcher partnerships is crucial for advancing health equity and scientific discovery.