The Effect of Moringa oleifera on Body Weight and Blood Pressure: A Systematic Review and Meta-Analysis of Randomized
Mahnoush Mehrzad Samarin1, Fatemeh Sheikhhossein2, Amir Hossein Khalilkhaneh2
1Department of Physical Education and Sport Sciences, Science and Research Branch Islamic Azad University Tehran Iran.
Abstract:
Moringa oleifera is suggested as an antihypertensive and anti-obesity agent, but there is insufficient evidence to establish a causal link between Moringa oleifera and reductions in blood pressure and body measurements in humans. This systematic review and meta-analysis seek to examine the effects of Moringa oleifera on body weight and blood pressure. A search was conducted through Web of Science, Scopus, and PubMed, along with a manual review of bibliographies, for articles published up to July 2024. Out of 2295 articles, eight randomized controlled trials (RCTs) were included. The results indicated that Moringa oleifera consumption significantly reduced systolic blood pressure (SBP) by weighted mean differences (WMDs): -6.00 mmHg, p < 0.001 and diastolic blood pressure (DBP) by WMD: -7.32 mmHg, p < 0.001. However, no significant changes were observed in body mass index (BMI) (p = 0.435) and body weight (p = 0.938) compared to those who did not consume Moringa oleifera. Subgroup analyses revealed that SBP significantly decreased in adults consuming 5-10 g/day of Moringa oleifera, particularly in individuals with a BMI below 29.9 and those treated for more than 4 weeks. Furthermore, Moringa oleifera intake was linked to a significant reduction in DBP among participants taking < 10 g/day, those who were overweight, and individuals who supplemented for over 4 weeks. Our systematic review and meta-analysis of RCT indicated that Moringa oleifera had a significant impact on blood pressure, but it did not affect body weight or BMI. Further research is necessary to confirm these findings.
Related Concept Videos
Factors affecting Blood pressure
Physiological Factors:
Hypertension and Regulation of Blood Pressure
Hormonal Regulation of Blood Pressure
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction while...
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension II: Pathophysiology
