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Three-Year Visual Quality Evaluation in Children Using Orthokeratology Lenses: A Retrospective Study With OPD-Scan
Shang Li1, Yihan Guo1, Lei Tian1
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, 100730, China, trhos.com.
Journal of Ophthalmology
|June 8, 2026
Summary
Long-term orthokeratology (ortho-k) lens wear improved visual quality in children with myopia. This myopia control method showed a favorable safety profile over three years, with no vision-threatening complications.
Area of Science:
- Ophthalmology
- Optometry
- Corneal Refractive Therapy
Background:
- Myopia is a growing public health concern in children.
- Orthokeratology, or ortho-k, offers a non-surgical approach to myopia management.
- Corneal refractive therapy (CRT) lenses are a type of ortho-k used for myopia control.
Purpose of the Study:
- To assess long-term visual quality outcomes in children wearing CRT lenses.
- To evaluate refractive changes and safety associated with CRT lens wear over three years.
- To analyze the impact of CRT on ocular and intraocular aberrations.
Main Methods:
- Retrospective analysis of 130 myopic children (aged 8-18) using CRT lenses.
- Ocular examinations included visual acuity, refractive error, axial length, and visual quality parameters.
- Data collected at baseline, 1.5 years, and 3 years; analyzed using repeated measures ANOVA and Bonferroni tests.
Main Results:
- Slight increases in myopic refractive error and axial length observed over 3 years.
- Significant improvement in overall ocular visual quality (Strehl ratio, MTF) and decrease in total aberrations (RMS).
- Increased corneal aberrations (HOA, SA, coma, tilt) noted, particularly in the 5-mm zone, while intraocular aberrations decreased significantly. No safety concerns like microbial keratitis were reported.
Conclusions:
- Long-term CRT lens wear enhances visual quality despite increased corneal aberrations.
- Observed refractive and axial length changes align with previous ortho-k studies.
- CRT lenses demonstrate a safe and effective option for myopia management in children.

