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Updated: Jun 9, 2026
An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
The Correlation of the Perfusion Index with Pain Scales in Infants Undergoing Surgery
Razieh Sangsari1, Maryam Saeedi1, Kayvan Mirnia1
1Department of Pediatrics, Division of Neonatology - School of Medicine, Tehran University of Medical Sciences, Children's Medical Center, Tehran, Iran.
Background:
The Perfusion Index (PI) is considered an important tool for evaluating the condition of infants, but there are few studies on the correlation between PI and pain assessment in infants. Therefore, this study aimed to investigate the correlation between PI and pain scale in infants undergoing surgery.
Materials And Methods:
This prospective, cross-sectional study was conducted in the Neonatal Intensive Care Unit (NICU) of the Children's Medical Center in Tehran, Iran, between April 2020 and April 2023. Using the Crying Requires, Oxygen, Increased vital signs, Expression, and Sleeplessness and right-hand mean PI, using a Masimo pulse oximeter, pain scales were recorded immediately after surgery in the NICU and every 4 h for a total of 24 h by a skilled nurse unaware of the study. The correlation between PI and factors such as age, weight, NICU admission length, and pain scale was analyzed.
Results:
Our study found an inverse correlation between the pain scale and PI (p < 0.05; r: -0.385). Additionally, age, gestational age, and PI had a positive correlation with weight (p < 0.05; r: 0.233, 0.132, and 0.044, respectively). The age of the infant was also correlated with PI (p < 0.05; r: 0.307). Moreover, NICU admission length was inversely related to the PI scale (p < 0.05; r: -0.119).m.
Conclusions:
The ease of use and objective measurement method of the PI makes it a valuable nursing tool for pain measurement in infants, in addition to other methods. However, further studies are needed to confirm the effectiveness of this correlation.
