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Case Report: Recurrent Guillain-Barré Syndrome in a 56-Year-Old Male
Farah Sadiq1, Shayan Nawaz2, Moeez Ahmad Saeed3
1Department of Internal Medicine Lahore General Hospital Lahore Punjab Pakistan.
Clinical Case Reports
|June 8, 2026
Summary
Recurrent Guillain-Barré syndrome (GBS), an uncommon immune-mediated neuropathy, can present with distinct episodes. Early recognition and immunotherapy are crucial for managing this condition.
Area of Science:
- Neurology
- Immunology
- Clinical Case Reports
Background:
- Recurrent Guillain-Barré syndrome (GBS) is a rare variant of immune-mediated polyradiculoneuropathy.
- Distinguishing recurrent GBS from other demyelinating neuropathies is clinically significant.
Purpose of the Study:
- To report a case of recurrent GBS in a 56-year-old male.
- To highlight the diagnostic and therapeutic considerations in recurrent GBS.
Main Methods:
- Case report of a patient with two distinct episodes of demyelinating neuropathy.
- Clinical presentation, nerve conduction studies, and treatment response were documented.
- Infectious and metabolic workups were performed.
Main Results:
- The patient experienced two episodes of ascending paralysis and areflexia within 3 months.
- Nerve conduction studies consistently showed marked demyelination.
- Both episodes responded to plasma exchange, with no need for ventilatory support.
Conclusions:
- Recurrent GBS requires prompt recognition and appropriate immunotherapy.
- Differentiating recurrent GBS from acute-onset chronic inflammatory demyelinating polyneuropathy (CIPD) is essential for effective management.
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