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Related Experiment Videos

High Versus Low Radiographic Burden Odontogenic Sinusitis: Culture, Histopathology, and Patient-Reported Outcomes.

Landon E Ebbert1, Nitish Kumar2, Devyani Lal2

  • 1Mayo Clinic Alix School of Medicine-Arizona Campus Phoenix Arizona USA.

Laryngoscope Investigative Otolaryngology
|June 8, 2026
PubMed
Summary

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Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture01:26

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture

Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...

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High radiographic burden odontogenic sinusitis (ODS) is linked to older patients and increased inflammation. Endoscopic sinus surgery improved symptoms significantly in these patients, suggesting radiographic burden is important for ODS treatment decisions.

Area of Science:

  • Otolaryngology
  • Radiology
  • Pathology

Background:

  • Odontogenic sinusitis (ODS) presents with varying severity, from localized maxillary disease to pansinusitis.
  • Understanding the factors influencing ODS presentation and treatment outcomes is crucial for effective patient management.

Purpose of the Study:

  • To compare patient characteristics, microbial and histopathological features, and symptom outcomes after endoscopic sinus surgery (ESS) between ODS patients with low and high radiographic burden.

Main Methods:

  • Retrospective review of ODS patients undergoing ESS (01/2013-08/2024).
  • Classification into high or low radiographic burden based on preoperative CT scans (ostiomeatal complex opacification).
  • Analysis of demographic, microbiological, histopathological data, and pre/post-operative SNOT-22 scores.
Keywords:
endoscopic sinus surgeryhistopathologyodontogenic sinusitis

Related Experiment Videos

Main Results:

  • High radiographic burden ODS (70 patients) was associated with older age, higher inflammation, and specific epithelial changes compared to low burden ODS (17 patients).
  • Classic ODS bacterial profiles did not correlate with CT disease burden.
  • Significant symptom improvement (SNOT-22 scores) post-ESS was observed exclusively in the high radiographic burden group.

Conclusions:

  • High radiographic burden in ODS correlates with patient age and tissue inflammation.
  • Bacterial profiles do not appear to predict radiographic ODS severity.
  • Radiographic burden may be a significant factor in clinical decision-making for ODS management and warrants further investigation.