Advanced Adsorbents for Solid-Phase Extraction of Parabens: Progress and Prospects in Trace Analysis

Area of Science:

• Analytical Chemistry
• Materials Science

Background:

• Parabens are common preservatives with endocrine-disrupting properties and environmental persistence.
• Concerns about paraben toxicity and ecological impact necessitate sensitive detection methods.

Purpose of the Study:

• To systematically review solid-phase extraction (SPE) adsorbents for paraben enrichment and trace analysis.
• To evaluate advanced materials and their adsorption mechanisms for paraben detection.

Main Methods:

• Comprehensive literature search for SPE adsorbents developed in the last decade.
• Analysis of adsorption mechanisms including π-π interactions and hydrogen bonding.
• Critical evaluation of adsorbent performance across various sample matrices.

Main Results:

• Coverage of advanced adsorbents: covalent organic frameworks (COFs), molecularly imprinted polymers (MIPs), metal-organic frameworks (MOFs), and carbon-based nanomaterials.
• Assessment of strengths, limitations, and practical applicability of reviewed materials.
• Comparison of adsorbent performance in different environmental and biological samples.

Conclusions:

• Identification of key trends and future directions in SPE adsorbent development for paraben analysis.
• Recommendations for optimizing analytical conditions and material design for enhanced sensitivity and selectivity.
• Emphasis on developing robust and efficient methods for trace paraben detection to address health and environmental concerns.