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Related Concept Videos

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Decision Making: P-value Method

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Related Experiment Video

Updated: Jun 11, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.

Adam B Greenbaum1, John T D'Angelo1, Robert J Lederman2

  • 1Structural Heart and Valve Center, Emory University Hospital, Atlanta, Georgia, USA.

JACC. Cardiovascular Interventions
|June 9, 2026
PubMed
Summary
This summary is machine-generated.

Leaflet modification techniques are crucial for structural interventionalists. New algorithms guide the selection of aortic and mitral leaflet modification procedures based on patient anatomy and pathology.

Keywords:
BASILICABATMANLAMPOONUNICORNleaflet modification

Related Experiment Videos

Last Updated: Jun 11, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Area of Science:

  • Cardiovascular intervention
  • Structural heart disease management

Background:

  • Leaflet modification is essential for structural interventionalists.
  • Existing leaflet splitting techniques have limitations in extreme cases.
  • Emerging intraleaflet techniques offer broader applicability but raise safety concerns.

Purpose of the Study:

  • To propose systematic algorithms for aortic and mitral leaflet modification.
  • To guide structural operators in selecting appropriate leaflet modification approaches.

Main Methods:

  • Development of systematic algorithms for leaflet modification procedures.
  • Consideration of patient anatomy, pathology, and procedural goals in algorithm design.

Main Results:

  • Algorithms provide a structured approach to leaflet modification.
  • Guidance for selecting between leaflet splitting and intraleaflet techniques.

Conclusions:

  • Systematic algorithms can aid in optimizing leaflet modification procedures.
  • These algorithms support informed decision-making for structural interventionalists.