Relationship between feeding milestones and comorbidities with the postnatal growth in preterm infants

Faith Bala1,2, Enas Alshaikh1,2, Sudarshan R Jadcherla3,4,5,6

  • 1The Innovative Infant Feeding Disorders Research Program, Nationwide Children's Hospital, Columbus, Oh, USA.

Insights

Achieving feeding milestones earlier in preterm infants is linked to better postnatal growth. Delays in feeding milestones correlate with slower growth and longer hospital stays for these vulnerable infants.

Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Growth and Development

Background:

  • Postnatal growth is critical for preterm infants.
  • Feeding milestones are key developmental markers.
  • Understanding the link between feeding and growth is essential for optimizing care.

Purpose of the Study:

  • To investigate the association between feeding milestones and postnatal growth in preterm infants.
  • To identify potential growth faltering risks related to feeding progression.

Main Methods:

  • Retrospective analysis of 77 infants born before 32 weeks' gestation.
  • Growth z-scores calculated at birth and discharge.
  • Postnatal growth faltering (PGF) defined by significant z-score changes.

Main Results:

  • 11.7% severe and 22% complex PGF observed.
  • Infants born <28 weeks had higher PGF rates and feeding delays.
  • Delayed enteral feeding correlated with slower growth and longer hospitalization.

Conclusions:

  • Feeding milestones and postnatal growth are interconnected in preterm infants.
  • Early achievement of feeding milestones may promote improved growth outcomes.
  • Optimizing feeding strategies could enhance growth in this population.
Abstract

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...