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Updated: Jun 11, 2026
07:10
Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Use of Home Spirometry for Steroid Tapering
Zayan Musa1, Carson Tyler Moss2, Carlos Daniel Hernandez Borges3
1Department of Medicine University of California at Riverside Riverside California USA.
Respirology Case Reports
|June 10, 2026
Summary
Organising pneumonia (OP) is a lung complication after haematopoietic cell transplant (HCT). Weekly home spirometry aided successful prednisone tapering in a patient with OP and chronic graft-versus-host-disease (cGVHD).
Area of Science:
- Pulmonology
- Hematology
- Transplantation Medicine
Background:
- Organising pneumonia (OP) is a non-infectious pulmonary complication post-haematopoietic cell transplant (HCT).
- OP can be associated with chronic graft-versus-host-disease (cGVHD), requiring prolonged corticosteroid treatment.
- Corticosteroid therapy presents challenges, including dose-limiting toxicities and exacerbations during tapering.
Purpose of the Study:
- To report a case of OP associated with cGVHD.
- To illustrate the utility of home spirometry in managing prednisone tapering.
- To demonstrate successful reduction of prednisone dose while maintaining stability.
Main Methods:
- A case study of a 43-year-old male with OP and cGVHD.
- Utilized weekly home spirometry for close pulmonary function monitoring.
- Guided prednisone dose reduction based on spirometry trends and clinical status.
Main Results:
- The patient experienced difficulties tapering prednisone due to frequent OP exacerbations.
- Weekly home spirometry facilitated successful prednisone dose reduction by 80%.
- Clinical and functional stability was maintained throughout the tapering process.
Conclusions:
- Home spirometry is a valuable tool for monitoring pulmonary function in OP patients post-HCT.
- This approach can aid in successfully guiding corticosteroid tapering, even in complex cases like cGVHD.
- Effective management of OP exacerbations allows for significant prednisone dose reduction and improved patient stability.
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