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Cooperative B(C6F5)3/Chiral Secondary Amine-Catalyzed Asymmetric [4 + 2] Cycloaddition Reaction

Dan-Dan Ma1, Li-Xue Xiong1, Wen-Jing Wang1

  • 1Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei Key Laboratory for Precision Synthesis of Small Molecule Pharmaceuticals, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P. R. China.

Organic Letters
|June 10, 2026
PubMed
Summary

A novel cycloaddition reaction creates complex spirooxindole compounds with high stereoselectivity. This method utilizes synergistic catalysis for efficient synthesis under mild conditions.

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