Related Experiment Video
Updated: Jun 12, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Broken Links: Gender Disparities Across the Chain of Survival in Out-Of-Hospital Cardiac Arrest
Rylie Rasmussen1, Adrianna Watson1
1College of Nursing, Brigham Young University, Provo, Utah, USA.
Aim(S):
To examine gender-based disparities across each link of the American Heart Association's Chain of Survival for women experiencing out-of-hospital cardiac arrest, highlighting systemic, cultural and educational barriers that compromise equitable outcomes.
Design:
A discursive review synthesizing epidemiological studies, public health data and qualitative research on cardiac arrest and gender disparities.
Methods:
A comprehensive search of databases including PubMed and CINAHL identified studies on gender differences in out-of-hospital cardiac arrest recognition, bystander intervention, emergency response and post-arrest care. Literature was critically analyzed using constant comparative analysis and organized according to the five links of the American Heart Association's Chain of Survival to identify recurring themes and evidence of disparity.
Results:
Significant disparities were identified at every link in the Chain of Survival. Women are less likely to have cardiac symptoms recognized, receive bystander cardiopulmonary resuscitation or defibrillation and experience timely or guideline-concordant advanced life support and post-resuscitation care. Contributing factors include implicit bias, underrepresentation of women in resuscitation training materials and social norms that hinder rapid intervention.
Conclusion:
Gender disparities in cardiac arrest survival are systemic and multifactorial, resulting in 'broken links' across emergency response systems, public perceptions and healthcare education. Addressing these inequities requires reforms in public education, resuscitation training and clinical protocols that prioritize gender-sensitive and inclusive care.
Implications For The Profession And/Or Patient Care:
Nurses, as educators, advocates and caregivers, are uniquely positioned to drive transformational change in emergency and cardiac care. By championing women-centered and gender-sensitive resuscitation education, implementing inclusive practices and addressing intersectional barriers, nurses can help ensure equitable, responsive and just care. Advancing these priorities is essential for improving survival and neurological outcomes for women and advancing health equity in global healthcare.
Reporting Method:
We adhered to the principles of the EQUATOR guidelines. This discursive paper did not meet the criteria for a specific standardized checklist.
Patient Or Public Contribution:
No patient or public involvement. This study did not include patient or public involvement in its design, conduct or reporting.
More Related Videos
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
05:36Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Published on: January 30, 2020
Related Concept Videos
Cardiopulmonary Resuscitation I: Adult
Introduction Cardiac Emergencies
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation III: AED Use
Acute Coronary Syndrome IV: Interprofessional Care