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Understanding the Importance, Utility, and Responsible Application of the H-index in Orthopedics

Sachin Kale1, Vishnu Senthil2, Mainak Roy3

  • 1Department of Orthopaedics, D. Y. Patil University School of Medicine, Navi Mumbai, Maharashtra, India.

Journal of Orthopaedic Case Reports
|June 11, 2026
PubMed
Abstract

No abstract available in PubMed .

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The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...