Procollagen 1 assembles into phase-separated condensates in the endoplasmic reticulum.

Soumya Bhattacharyya1, Jose Wojnacki1, Nathalie Brouwers1

  • 1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology , Barcelona, Spain.

Summary

Procollagen I (PC1) forms biomolecular condensates in the endoplasmic reticulum (ER) of activated hepatic stellate cells. This organization aids PC1 export without triggering ER stress or degradation.

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