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Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
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Development of multicenter consensus care plans for immunosuppression after pediatric liver transplant: Reducing variability, creating comparative efficacy opportunities.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·2026
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AASLD AST NASPGHAN Practice Guideline on pediatric liver transplantation: Post-transplant management.

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OPTN/SRTR 2024 Annual Data Report: Overview of US Solid Organ Transplantation.

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OPTN/SRTR 2024 Annual Data Report: Pancreas.

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OPTN/SRTR 2024 Annual Data Report: Liver.

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OPTN/SRTR 2024 Annual Data Report: Kidney.

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Tolerance meets regenerative medicine: A new route to donor-specific allograft acceptance?

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Comment on "Living donor liver transplant is associated with lower hospitalization costs than deceased donor liver transplant: a multicenter cohort study of young children transplanted for biliary atresia".

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Paclitaxel-Coated Balloon Therapy for Refractory Ureteral Stenosis in a Kidney Transplant Recipient.

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Updated: Jun 13, 2026

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
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Published on: February 10, 2017

OPTN/SRTR 2024 Annual Data Report: Intestine.

Simon P Horslen1, Vikram K Raghu2, David P Schladt3

  • 1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Pediatrics, University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|June 11, 2026
PubMed
Summary
This summary is machine-generated.

Intestine transplants are crucial for various conditions, with survival rates varying based on liver involvement. In 2024, 128 new candidates joined the waiting list, highlighting the growing need for this life-saving procedure.

Keywords:
Intestinal failureintestine transplantintestine-liver transplantoutcomespediatricwaiting list

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ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
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09:40

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Published on: April 17, 2020

Area of Science:

  • Transplantation surgery
  • Gastroenterology
  • Immunology

Background:

  • Intestine transplantation is a complex procedure for diverse conditions impacting quality of life.
  • Transplants can be performed with or without a liver transplant, sometimes including other organs like the stomach, pancreas, or colon.
  • In 2024, 128 individuals were added to the US intestine transplant waiting list, with short-gut syndrome being common, but motility disorders, mesenteric thromboses, and tumors increasingly prevalent.

Purpose of the Study:

  • To analyze the 2024 trends in intestine transplant waiting lists and outcomes.
  • To compare graft survival rates for intestine-only versus intestine-with-liver transplants.
  • To report on acute rejection rates in recent intestine transplant recipients.

Main Methods:

  • Analysis of waiting list data from 2024, including demographics and diagnoses.
  • Review of graft survival statistics for adult and pediatric recipients from 2017-2019.
  • Examination of acute rejection rates within the first year post-transplant for recent cohorts.

Main Results:

  • In 2024, 97 intestine transplants were performed, with 32 in pediatric recipients.
  • No deaths were reported on the waiting list for intestine-without-liver transplants, contrasting with 11 deaths for intestine-with-liver transplants.
  • 1- and 5-year graft survival rates differed significantly between intestine-only and intestine-with-liver transplants, and between adult and pediatric recipients.
  • 44% of the most recent cohort experienced acute rejection within the first year.

Conclusions:

  • Intestine transplant remains a vital option for patients with severe gastrointestinal conditions.
  • Outcomes and waiting list mortality vary significantly depending on whether a liver transplant is included.
  • The expanding indications and evolving demographics for intestine transplantation necessitate ongoing monitoring and research.