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Why Renal Cancer Guidelines Should be Tailored to Histologic Subtype
Andrea Pettit1, Ali J Hajiran1, Steven C Campbell1
1Department of Urology, West Virginia University School of Medicine, Morgantown, WV, USA.
European Urology Oncology
|June 11, 2026
Summary
Non-clear cell renal cell carcinoma (nccRCC) differs from clear cell RCC, often recurring late or in the abdomen. Current surveillance methods for nccRCC have notable strengths and weaknesses.
Area of Science:
- Oncology
- Urology
- Nephrology
Background:
- Non-clear cell renal cell carcinoma (nccRCC) exhibits distinct biological behavior compared to clear cell renal cell carcinoma (ccRCC).
- nccRCC is associated with a higher incidence of late recurrences and abdominal relapse patterns.
- Effective surveillance strategies are crucial for managing nccRCC post-treatment.
