Related Experiment Video
Updated: Jun 13, 2026
08:30
Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
Clinical Factors Associated with Brucella-Related Epididymo-Orchitis: A Retrospective Cohort Study
Yakup Gezer1, Muhammet Rıdvan Tayşi1
1Infectious Diseases and Clinical Microbiology Clinic, University of Health Sciences, Konya City Hospital, Konya 42020, Türkiye.
Journal of Clinical Medicine
|June 12, 2026
Summary
Brucella-related epididymo-orchitis (BEO) affects 16.8% of male brucellosis patients, particularly younger individuals with fever and shorter symptom duration. Early consideration of BEO is crucial in endemic areas for patients with acute scrotal symptoms.
Area of Science:
- Infectious Diseases
- Urology
- Epidemiology
Background:
- Brucella-related epididymo-orchitis (BEO) is a frequent genitourinary complication of brucellosis.
- Understanding BEO's clinical and epidemiological profile is essential for timely diagnosis and management.
Purpose of the Study:
- To evaluate the clinical and epidemiological characteristics of BEO in male brucellosis patients.
- To identify clinical factors associated with the development of BEO.
Main Methods:
- Retrospective single-center cohort study.
- Comparison of epidemiological, clinical, and laboratory data between male brucellosis patients with and without BEO.
- Multivariate logistic regression to determine independent predictors of BEO.
Main Results:
- BEO was diagnosed in 16.8% of 262 male brucellosis patients.
- Younger age, presence of fever, and shorter symptom duration were associated with BEO.
- Higher leukocyte counts and C-reactive protein levels were observed in patients with BEO.
Conclusions:
- BEO is a significant complication in male brucellosis patients.
- Younger age, shorter symptom duration, and fever are key indicators for BEO.
- BEO should be considered in the differential diagnosis of acute scrotal symptoms in endemic regions.
Related Concept Videos
01:26Factors Affecting the Risk of Infection
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
01:28Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
01:26Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
01:18Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
01:23Infertility in Males
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...