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Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

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Related Experiment Video

Updated: Jun 13, 2026

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis
09:22

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis

Published on: May 12, 2020

Infectious Keratitis: A Retrospective Analysis of a Tertiary Care Center.

Jana Schaetzel1, Taos Batal1, Marcus Walckling1

  • 1Department of Ophthalmology, University Medical Center Rostock, 18057 Rostock, Germany.

Journal of Clinical Medicine
|June 12, 2026
PubMed
Summary
This summary is machine-generated.

Infectious keratitis treatment outcomes varied by pathogen, with viral, fungal, and parasitic infections showing significant visual acuity improvement. Early diagnosis and prompt therapy are crucial for better visual prognosis.

Keywords:
Acanthamoeba keratitisbacterial keratitisfungal keratitisinfectious keratitisviral keratitis

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Last Updated: Jun 13, 2026

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis
09:22

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Published on: May 12, 2020

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Infectious keratitis poses a significant threat to vision.
  • Pathogen prevalence and characteristics of infectious keratitis differ geographically.

Purpose of the Study:

  • To characterize risk factors, clinical presentations, and treatment outcomes for infectious keratitis in the Rostock area.
  • To compare treatment outcomes across different causative pathogens (viral, bacterial, fungal, parasitic).

Main Methods:

  • Retrospective analysis of 65 patients with infectious keratitis.
  • Minimum three-month follow-up period.
  • Assessment of visual acuity changes and treatment modalities (medical vs. surgical).

Main Results:

  • Viral, fungal, and parasitic keratitis groups showed statistically significant improvements in visual acuity.
  • Bacterial keratitis did not achieve statistical significance in visual acuity improvement.
  • No significant difference in final visual acuity was observed between medical and surgical treatments across all pathogen groups.

Conclusions:

  • Treatment modality (medical vs. surgical) did not demonstrate superiority in visual outcomes for infectious keratitis.
  • Timely diagnosis and initiation of appropriate therapy are critical for improving visual prognosis and minimizing complications.