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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

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Related Experiment Video

Updated: Jun 13, 2026

Venous Thrombosis Assay in a Mouse Model of Cancer
04:40

Venous Thrombosis Assay in a Mouse Model of Cancer

Published on: January 5, 2024

When Cancer Clots: An Extensive Radiologic Analysis of Cancer-Associated Thromboembolism.

Joshua Brooks1, Ola A E Mohamed2, Julia H Miao1

  • 1Department of Radiology, University of Chicago, Chicago, IL 79409, USA.

Cancers
|June 12, 2026
PubMed
Summary
This summary is machine-generated.

Cancer-associated thrombosis (CAT) significantly increases morbidity and mortality. Radiologists play a crucial role in diagnosing and managing venous and arterial events, guiding therapy with advanced imaging and an integrated approach.

Keywords:
FDG-PETarterial thromboembolismcancer-associated thrombosisincidental thromboembolisminterventional radiologytumor thrombusvenous thromboembolism

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Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
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Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

Area of Science:

  • Radiology
  • Oncology
  • Vascular Medicine

Background:

  • Cancer-associated thrombosis (CAT) is a major cause of death in cancer patients.
  • Patients with cancer have a significantly higher risk of both venous and arterial thromboembolism.
  • Imaging manifestations of CAT extend beyond deep vein thrombosis and pulmonary embolism.

Purpose of the Study:

  • To review the full spectrum of imaging findings in cancer-associated thrombosis.
  • To highlight the radiologist's role in detection, characterization, and therapeutic guidance for CAT.
  • To discuss diagnostic challenges and emerging imaging techniques for thrombus characterization.

Main Methods:

  • Comprehensive review of imaging manifestations of CAT.
  • Discussion of diagnostic challenges, including differentiating bland from tumor thrombus.
  • Exploration of advanced imaging techniques (e.g., diffusion-weighted MRI, contrast-enhanced ultrasound, FDG-PET/CT) and AI/ML applications.
  • Review of interventional radiology techniques for CAT management.

Main Results:

  • CAT encompasses venous thromboembolism, unusual-site thromboses, arterial events, and catheter-related complications.
  • Distinguishing bland from tumor thrombus is critical for cancer staging and treatment planning.
  • Advanced imaging and AI/ML offer improved thrombus characterization and patient selection.
  • Interventional radiology provides essential management strategies, especially for high-bleeding-risk patients.

Conclusions:

  • Effective management of CAT requires a synthesized, oncology-informed interpretive approach by radiologists.
  • Radiologists are central to oncologic care, integrating imaging findings with patient history and risk profiles.
  • Systematic attention to cardiovascular structures is needed due to increased cancer-associated arterial disease.