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Updated: Jun 13, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
Published on: September 22, 2023
Characteristics Associated with Infant Feeding with Both Breast Milk and Formula Milk
Kenta Watakabe1, Sayaka Kawada1, Shin Horiuchi1
1Division of Pediatrics, Tokyo Metropolitan Toshima Hospital, 33-1 Sakaecho Itabashiku, Tokyo 173-0015, Japan.
Mixed feeding infant strategies vary significantly. Late preterm birth, advanced maternal age, and cesarean delivery are linked to increased formula intake, informing targeted breastfeeding support interventions.
Area of Science:
- Pediatrics
- Neonatal Care
- Public Health Nutrition
Background:
- Breastfeeding offers significant maternal and infant health benefits.
- Promoting breastfeeding is a key public health objective.
- Infant feeding strategies encompass exclusive breastfeeding, mixed feeding, and exclusive formula feeding.
Purpose of the Study:
- To characterize heterogeneous mixed feeding patterns in infants.
- To identify factors associated with formula intake in mixed feeding.
- To inform tailored interventions for breastfeeding promotion.
Main Methods:
- Analysis of 2628 infants born at Tokyo Metropolitan Hospital (2019-2024).
- Gaussian mixture modeling to determine mixed feeding subgroups.
- Linear regression to identify factors influencing formula intake.
Main Results:
- Mixed feeding (56.9%) was the most common feeding strategy.
- Late preterm birth, maternal age (≥35 years), and cesarean delivery significantly increased formula intake.
- Exclusive breastfeeding (32.0%) and exclusive formula feeding (11.0%) were also observed.
Conclusions:
- Mixed feeding is not a monolithic category; distinct subgroups exist.
- Interventions should address identified factors like late preterm birth, maternal age, and delivery mode.
- Understanding these factors can enhance the promotion of breastfeeding.
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