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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Short-term functional outcome and pain assessment after spinal decompression for spondylodiscitis
Bogdan Șendrea1,2, Bogdan Gabriel Voicu1,2, Sebastian Mihai Valeanu1,2
1Foisor Clinical Hospital of Orthopedics, Traumatology and Osteoarticular Tuberculosis, Bucharest, Romania.
Journal of Medicine and Life
|June 12, 2026
Summary
Surgical treatment for spondylodiscitis effectively relieves pain and improves function. Early microbiological diagnosis during decompression surgery is crucial for targeted therapy and preventing antibiotic resistance.
Area of Science:
- Spinal surgery
- Infectious diseases
- Microbiology
Background:
- Spondylodiscitis is a rare but severe spinal infection potentially leading to disability or death.
- Infections can be pyogenic (e.g., Staphylococcus aureus), granulomatous (e.g., tuberculosis, fungal), or parasitic.
- Pain and neurological deficits arise from bone destruction, deformity, and mass effect.
Purpose of the Study:
- To evaluate the efficacy of posterior decompression surgery, instrumental fixation, and deformity correction in treating spondylodiscitis.
- To assess the impact of surgical intervention on pain, neurological deficits, and functional outcomes.
- To emphasize the importance of microbiological diagnosis for guiding treatment.
Main Methods:
- Retrospective study of 67 patients with spondylodiscitis between February 2013 and May 2020.
- Patients underwent posterior decompression, specimen collection for microbiology, transpedicular fixation, and deformity correction.
- Inclusion criteria: spinal pain, neurological deficit, radiological confirmation, and positive microbiology. Exclusions: <18 years, multiple surgeries, degenerative or conservative cases.
Main Results:
- Lumbar involvement was most common (73.13%).
- Pain scores (VAS) significantly improved at 6 weeks and 3 months post-surgery.
- All patients showed functional improvement in Oswestry Disability Index and Frankel grades post-operatively.
Conclusions:
- Surgical intervention is effective for pain relief, deformity correction, and functional improvement in spondylodiscitis.
- Obtaining microbiological diagnosis during decompression is critical for targeted therapy.
- Accurate diagnosis aids in minimizing antibiotic resistance and optimizing patient outcomes.