Comparative evaluation of nano-hydroxyapatite dentifrice, diode laser alone and combined for dentin hypersensitivity:...

Dentin hypersensitivity is a common clinical condition characterized by short, sharp pain arising from exposed dentinal tubules, posing a challenge for long-term management. This randomized, single-blind parallel-arm clinical trial evaluated and compared the effectiveness of nano-hydroxyapatite (N-HAP) dentifrice and diode laser used alone and in combination, with fluoride dentifrice as a control. Fifty-five hypersensitive sites were allocated into four groups and sensitivity was assessed using VAS and VDS scores at baseline, immediately post- treatment and at 1, 4 and 8 weeks. All test groups demonstrated a significant reduction in dentin hypersensitivity compared to the control group, with the combination therapy showing the greatest and most sustained reduction. The combined use of N-HAP dentifrice and diode laser exhibits a superior synergistic effect, indicating its potential as an effective approach for managing dentin hypersensitivity.