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Related Experiment Video

Updated: Jun 13, 2026

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
04:44

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

Published on: July 21, 2021

NeuroCaptain v2 - Interactive Three-Dimensional fNIRS Optode and Probe Montage Design Platform Based on Blender.

Ashlyn McCann1, Qianqian Fang1,2

  • 1Northeastern University, Department of Bioengineering, Boston, Massachusetts, United States.

Biorxiv : the Preprint Server for Biology
|June 12, 2026
PubMed
Summary

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NeuroCaptain v2 enhances functional near-infrared spectroscopy (fNIRS) neuroimaging by offering an open-source, 3D tool for precise optode placement. This reduces cross-subject variability, improving data reproducibility and analysis accuracy.

Area of Science:

  • Neuroimaging
  • Biomedical Engineering
  • Neuroscience

Background:

  • Accurate optode placement is critical for high-quality functional near-infrared spectroscopy (fNIRS) data.
  • Conventional 2D-to-3D transformation methods introduce significant placement variability across subjects and head surfaces.

Purpose of the Study:

  • Introduce NeuroCaptain v2, an open-source Blender add-on for interactive, anatomically guided fNIRS optode design and registration.
  • Enable precise 3D optode placement and cortical sensitivity visualization for fNIRS studies.

Main Methods:

  • Utilize Blender's physics simulation for mechanical constraints in probe layout.
  • Integrate mesh-based Monte Carlo (MMC) and diffusion-solver Redbird for 3D sensitivity mapping.
  • Store optode layouts in barycentric coordinates on a 10-20 landmark mesh for cross-subject consistency.
Keywords:
10–20 systemBlenderfNIRSforward modelingmontage designopen-source

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fMRI Validation of fNIRS Measurements During a Naturalistic Task
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fMRI Validation of fNIRS Measurements During a Naturalistic Task

Published on: June 15, 2015

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
08:19

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels

Published on: October 20, 2023

Related Experiment Videos

Last Updated: Jun 13, 2026

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
04:44

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

Published on: July 21, 2021

fMRI Validation of fNIRS Measurements During a Naturalistic Task
10:36

fMRI Validation of fNIRS Measurements During a Naturalistic Task

Published on: June 15, 2015

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
08:19

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels

Published on: October 20, 2023

Main Results:

  • Demonstrate interactive 3D montage design and cross-head-atlas probe registration.
  • Achieve a mean per-optode standard deviation of 2.29 mm, a 74% reduction in placement variability compared to conventional methods.
  • Showcase visualization of cortical sensitivity across diverse head geometries.

Conclusions:

  • NeuroCaptain v2 offers a reproducible, open-source workflow for fNIRS probe montage design.
  • Facilitates anatomically guided probe development and cross-subject registration in a 3D environment.
  • Significantly improves the accuracy and reproducibility of fNIRS data acquisition.