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Updated: Jun 14, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state

Dandan Yang1, Linglin Huang1, Hanning Cheng1

  • 1Gene Lay Institute of Immunology and Inflammation, Harvard Medical School and Mass General Brigham, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02149, USA; Ann Romney Center for Neurologic Diseases, Harvard Medical School and Mass General Brigham, Boston, MA 02115, USA.

Immunity
|June 12, 2026
PubMed

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Keywords:
CNS autoimmunityCYP11A1Nrc31TGF-β1Th17glucocorticoidhomeostasissteroid resistance