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Published on: August 14, 2019
What is the Standard Comparator of Minimally Invasive Surgical Therapies (MIST) for Benign Prostatic Obstruction?
Michael Baboudjian1, Cosimo De Nunzio2, Dean Elterman3
1Department of Urology, North Academic Hospital, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Abstract:
The choice of comparator critically determines the interpretability and clinical relevance of trials evaluating minimally invasive surgical therapies (MISTs), with sham-controlled studies now considered insufficient for guideline integration. Active comparators, particularly pharmacological therapy and conventional surgery, provide the highest level of evidence, enabling a meaningful positioning of MISTs within the therapeutic algorithm of male lower urinary tract symptoms/benign prostatic obstruction.
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