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Contrast Echocardiography in the Multimodal Diagnosis of a Giant Primary Cardiac Angiosarcoma: A Case Report
Han Gao1, Haoyi Zhang1, Diandian Zhu1
1Department of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Insights
A rare cardiac angiosarcoma case highlights the diagnostic power of contrast echocardiography in identifying hypervascular malignancy. Multimodal imaging and pathology confirmed the diagnosis in a young woman with atypical symptoms.
Area of Science:
- Cardiology
- Oncology
- Diagnostic Imaging
Background:
- Cardiac tumors are rare, with angiosarcoma being the most common primary malignant type.
- Atypical presentations of cardiac angiosarcoma can delay diagnosis.
- Early and accurate diagnosis is crucial for patient management and outcomes.
Abstract:
We report the case of a 26-year-old woman presenting with atypical symptoms of palpitations and dizziness. Transthoracic echocardiography (TTE) revealed a large hypoechoic mass in the right atrium accompanied by pericardial effusion. Contrast echocardiography showed rapid, intense homogeneous enhancement within one cardiac cycle, suggesting hypervascular malignancy. Subsequent computed tomography (CT) and magnetic resonance imaging (MRI) confirmed the findings and excluded distant metastases. Following surgical excision of the mass, pathological and immunohistochemical analysis confirmed the diagnosis of angiosarcoma. The patient was started on postoperative AIM chemotherapy. This case demonstrates the diagnostic value of contrast echocardiography within multimodal imaging, especially in atypical presentations of cardiac angiosarcoma.
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