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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Dearomative [3,3]-Claisen Rearrangement of 2-Indolyl Alcohols: An Efficient and General Protocol for Synthesizing

Yu Nie1, Jian Sun1, Guan-Jiang Fan1

  • 1Key Laboratory of Applied Surface and Colloid Chemistry & School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, China.

Angewandte Chemie (International Ed. in English)
|June 13, 2026
PubMed

Keywords:
[3,3]‐Claisen rearrangementdearomatization of indoleindole alkaloidsnatural productstotal synthesis

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