Related Experiment Video
Updated: Jun 16, 2026
The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
Published on: September 7, 2022
Gluteal Muscle Degeneration Is Associated with Compensation Failure in Age-Related Spinopelvic Malalignment: A
Shizumasa Murata1, Hiroshi Hashizume1,2, Hiroshi Iwasaki1
1Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Introduction:
The role of pelvic stabilizing muscles, particularly the gluteus muscles, remains largely unexplored in the context of sagittal alignment. Understanding the relative vulnerability of each muscle group during the sequential breakdown of sagittal alignment is thus important. We hypothesize that gluteal muscle degeneration precedes or accompanies the failure of pelvic compensation in sagittal malalignment, making it a key indicator of early decompensation. Here, we examine which trunk or pelvic muscles demonstrate the greatest deterioration in morphology and quality across progressive stages of sagittal alignment decompensation, and aim to identify muscle-related predictors of spinopelvic malalignment.
Methods:
In this cross-sectional study, we analyzed 204 outpatients stratified into groups based on standing whole-spine radiographic parameters: normal (sagittal vertical axis [SVA] ≤50 mm and pelvic tilt [PT] ≤20°), compensated (SVA ≤50 mm and PT >20°), and decompensated (SVA >50 mm). We measured computed tomography-derived cross-sectional area (CSA) and Hounsfield unit (HU) values for the paravertebral (erector spinae and multifidus), psoas, gluteus medius, and gluteus maximus muscles. Group comparisons were performed using non-parametric tests, and logistic regression models were used to identify independent predictors of alignment deterioration.
Results:
Both gluteal and paraspinal muscles exhibited significant declines in CSA and HU values across worsening alignment stages, whereas the psoas muscle did not. In multivariate analyses, reduced HU values of the gluteus medius and maximus and decreased paraspinal CSA values were independently associated with abnormal and decompensated alignment. Notably, the gluteus medius HU value was positively associated with compensation maintenance, whereas the gluteus maximus HU value had a negative association.
Conclusions:
Degeneration of the gluteal muscles, especially in muscle quality, is strongly associated with the breakdown of sagittal alignment compensation. Our results suggest the gluteal musculature is a useful early biomarker and therapeutic target in preventing age-related spinal imbalance.
More Related Videos
06:28Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation
Published on: December 13, 2024
12:25C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
Published on: September 16, 2022
Related Concept Videos
01:26Cross-bridge Cycle
01:27Degenerative Disc Disease I: Introduction
01:20Muscles that Move the Thigh
Three other significant muscles are the gluteus maximus, gluteus medius, and gluteus minimus. The gluteus maximus originates from the posterior surface of the ilium, sacrum, and coccyx, and the thoracolumbar fascia...
01:23Degenerative Disc Disease ll: Pathophysiology
01:09Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...