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A Practical Reference for Stereotactic Radiosurgery Planning for Intracranial Indications
Ying Meng1, Elad Mashiach1, Bernadine Donahue2
1Department of Neurosurgery, NYU Grossman School of Medicine, New York, New York, USA.
Neurosurgery
|June 15, 2026
Summary
Stereotactic radiosurgery (SRS) offers precise radiation for brain conditions like tumors and functional disorders. This review guides neurosurgeons and radiation oncologists on SRS indications, techniques, and dose selection.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Medical Physics
Background:
- Stereotactic radiosurgery (SRS) has advanced significantly over 30 years.
- It is now a primary treatment for various intracranial conditions.
Purpose of the Study:
- To provide a comprehensive overview of SRS indications, evidence, and technical aspects.
- To serve as a reference for clinicians regarding dose selection and outcomes.
- To detail treatment parameters in tables for planning and clinical use.
Main Methods:
- Narrative review of current evidence.
- Analysis of technical considerations and controversies.
- Inclusion of tables summarizing indications, doses, and outcomes.
Main Results:
- SRS is a valuable, often first-line, treatment for brain tumors, vascular malformations, and functional disorders.
- Evidence supports SRS for a wide range of intracranial pathologies.
- Dose selection and technical nuances are critical for optimal outcomes.
Conclusions:
- Stereotactic radiosurgery is an established and evolving treatment modality.
- This review provides essential guidance for neurosurgeons and radiation oncologists.
- Clinicians can use the provided tables for informed treatment planning and patient management.
