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LWF-YOLO: a lightweight framework based YOLO for blood cell detection.
Rui Mao1, Dazhi Huang2, Yuanyuan Wu1
1School of Computer Science and Cyber Security, Chengdu University of Technology, No.1, East Third Road, Erxianqiao, Chengdu 610059, Sichuan, People's Republic of China.
Biomedical Physics & Engineering Express
|June 15, 2026
Summary
A new lightweight object detection framework, LWF-YOLO, enhances blood cell detection accuracy. This method improves diagnosis of hematological disorders by offering efficient and precise analysis on resource-constrained devices.
Area of Science:
- Medical imaging
- Computer vision
- Hematology
Background:
- Accurate blood cell detection is crucial for diagnosing hematological disorders like anemia and leukemia.
- Traditional methods face limitations in subjectivity and efficiency for complex cellular patterns.
Purpose of the Study:
- To introduce LWF-YOLO, a lightweight object detection framework for enhanced blood cell detection.
- To improve the accuracy and efficiency of automated hematological analysis.
Main Methods:
- Developed LWF-YOLO based on YOLOv11, incorporating a Multi-Scale Edge-Aware Feature Enhancement (MSEFE) module for cell boundary delineation.
- Introduced a Dynamic Channel-Mixing Gated Former (DCGFormer) and Dynamic Deformable Convolution Network (DyDCN) for optimized feature modulation and robust localization.
- Utilized Sobel operators, multi-scale fusion, identity mapping, dynamic channel splitting, adaptive gating, and multi-dimensional attention.
Main Results:
- LWF-YOLO achieved high mean average precision (mAP) in blood cell detection.
- Demonstrated competitive or superior performance compared to state-of-the-art models like YOLOv11 and RT-DETR-R18.
- Maintained a lightweight profile with minimal computational overhead, enabling efficient deployment.
Conclusions:
- LWF-YOLO offers a significant advancement in automated hematological analysis.
- The framework enables real-time diagnostics on resource-constrained devices, improving accessibility and speed.
- LWF-YOLO addresses the limitations of traditional methods by providing accurate and efficient blood cell detection.
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