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Impact of a multidisciplinary intervention and preoperative antibiotic room on surgical antimicrobial prophylaxis
Elif Nur Özbay Haliloğlu1, Zeynep Tekin Taş1
1Sincan Research and Training Hospital, Infectious Diseases and Clinical Microbiology Department, Ankara, Turkey.
Background:
Compliance with surgical antimicrobial prophylaxis (SAP) remains suboptimal worldwide, particularly regarding appropriate timing and duration. Inappropriate practices, including early administration and prolonged prophylaxis, contribute to antimicrobial resistance and increased health care costs. To evaluate the impact of a multidisciplinary intervention, including the implementation of a preoperative antibiotic room, on SAP compliance and its sustainability over time.
Methods:
This quasi-experimental pre-post study was conducted in a tertiary care hospital between 2022 and 2025. The intervention included establishing a preoperative antibiotic administration area, standardizing workflow processes, and providing regular education and feedback to surgical teams. SAP compliance was assessed according to national and international guidelines.
Results:
Overall SAP compliance improved significantly from 15.4% in the pre-intervention period to 56.1% in the sustainability period. Early antibiotic administration decreased from 68.2% to 20.1%, while prolonged prophylaxis (> 24 hours) declined from 45.5% to 25.8%. Improvements were consistent across surgical procedures and sustained over time.
Conclusions:
A structured multidisciplinary approach, including a dedicated preoperative antibiotic room and continuous feedback mechanisms, significantly improves SAP compliance. This model represents an effective and scalable strategy for enhancing guideline adherence and optimising antimicrobial use in surgical settings, with sustained improvement over time.
Insights
Implementing a preoperative antibiotic room and multidisciplinary approach significantly improved surgical antimicrobial prophylaxis (SAP) compliance. This strategy reduced early and prolonged antibiotic use, enhancing guideline adherence and optimizing antimicrobial stewardship.
Area of Science:
- Surgical infection prevention
- Antimicrobial stewardship
- Healthcare quality improvement
Background:
- Surgical antimicrobial prophylaxis (SAP) compliance is globally suboptimal.
- Inappropriate SAP timing and duration contribute to antimicrobial resistance and increased costs.
Purpose of the Study:
- To assess the impact of a multidisciplinary intervention on SAP compliance.
- To evaluate the sustainability of improved SAP practices over time.
- To determine the effect of a preoperative antibiotic room on SAP adherence.
Main Methods:
- Quasi-experimental pre-post study (2022-2025) in a tertiary care hospital.
- Intervention: preoperative antibiotic room, standardized workflows, education, and feedback.
- SAP compliance measured against national/international guidelines.
Main Results:
- Overall SAP compliance increased from 15.4% to 56.1%.
- Early antibiotic administration decreased from 68.2% to 20.1%.
- Prolonged prophylaxis (>24 hours) reduced from 45.5% to 25.8%, with sustained improvements.
Conclusions:
- A multidisciplinary approach with a dedicated antibiotic room enhances SAP compliance.
- This model effectively optimizes antimicrobial use in surgical settings.
- The strategy demonstrates scalability and sustained improvement in guideline adherence.
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