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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Mortality predictors in patients with ST-segment elevation myocardial infarction presenting no-reflow phenomenon

Larisa Renata Pantea-Roșan1,2, Ovidiu Țica3,4, Otilia Anca Țica1

  • 1Emergency County Clinical Hospital of Bihor, Cardiology Clinic, Gheorghe Doja Street, no. 65, Oradea, Bihor County, Romania.

Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne
|June 16, 2026
PubMed

Insights

The coronary no-reflow phenomenon significantly increases mortality risk in ST-elevation myocardial infarction (STEMI) patients post-primary percutaneous coronary intervention (PCI). Cardiovascular complications further elevate this risk, highlighting critical factors for STEMI patient outcomes.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Acute Myocardial Infarction Research

Background:

  • ST-segment elevation acute myocardial infarction (STEMI) is associated with increased mortality due to complications.
  • The no-reflow phenomenon, a complication following primary percutaneous coronary intervention (PCI), requires further investigation regarding its impact on mortality.

Purpose of the Study:

  • To determine the predictors of death and in-hospital mortality in STEMI patients experiencing the no-reflow phenomenon after primary PCI.
  • To analyze the specific risks associated with coronary versus myocardial no-reflow phenomena.

Main Methods:

  • A prospective study was conducted from January 2016 to March 2018, enrolling 656 STEMI patients.
  • The study focused on 96 STEMI patients who underwent primary PCI and subsequently developed the no-reflow phenomenon.

Main Results:

  • Mortality was significantly higher in anterior STEMI versus inferior STEMI (42.9% vs. 14.3%).
  • Mortality was significantly higher in the coronary no-reflow group compared to the myocardial no-reflow group (p=0.039).
  • Patients with post-PCI complications had substantially higher mortality rates (33.33%) than those without (1.75%, p<0.001).

Conclusions:

  • The coronary no-reflow phenomenon presents the highest mortality risk in STEMI patients post-PCI.
  • Cardiovascular complications in STEMI patients with the no-reflow phenomenon are associated with the majority of deaths.

Keywords:
ST elevation myocardial infarctionautopsymortalitymyocardial infarctionno-reflow phenomenonpercutaneous coronary interventionrisk factors

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