Emission dipole orientation reveals dynamic single-molecule interactions with 2D crystals at solvent interfaces

Wei Guo1, Tzu-Heng Chen2, Nathan Ronceray3

  • 1Laboratory of Nanoscale Biology, Institute of Bioengineering (IBI), School of Engineering (STI), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. wei.guo@epfl.ch.

Nature Communications
|June 16, 2026
PubMed
Summary

This study introduces polarized single-molecule localization microscopy to track both molecule location and orientation. This new method reveals molecular dynamics at solid-liquid interfaces, enabling precise control of quantum emitters.

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