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Updated: Jun 18, 2026

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An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
Patient-centered and technology-enabled strategies to improve tuberculosis treatment adherence
Malaisamy Muniyandi1, Sahil Abdul Salam1, Karikalan Nagarajan1
1ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Expert Review of Pharmacoeconomics & Outcomes Research
|June 17, 2026
Summary
Improving tuberculosis (TB) treatment adherence is crucial for disease control. Multicomponent strategies, including digital tools and community support, are most effective for sustained adherence and TB elimination.
Area of Science:
- Public Health
- Infectious Diseases
- Health Services Research
Background:
- Tuberculosis (TB) treatment adherence is critical for effective TB control.
- Poor adherence in high-burden countries like India leads to treatment failure, relapse, and drug-resistant TB (DR-TB).
Purpose of the Study:
- To review various strategies for improving TB treatment adherence.
- To synthesize evidence on the effectiveness of different adherence interventions.
Main Methods:
- A comprehensive literature search was conducted in PubMed and Google Scholar.
- Evidence from published literature on TB treatment adherence strategies was synthesized.
Main Results:
- Digital adherence technologies can enhance monitoring efficiency, reducing costs and resource intensity.
- Multicomponent strategies combining real-time monitoring, counseling, community engagement, and social support show promise.
Conclusions:
- Digital adherence strategies can complement existing TB programs by improving efficiency.
- Integrated, multicomponent approaches are essential for sustaining adherence, preventing drug resistance, and achieving TB elimination goals.
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