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Related Experiment Video

Updated: Jun 18, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

A new method for visualizing cerebrovascular vessels.

Qiang Gu¹, James Raymick¹, Sumit Sarkar¹

¹Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, United States.

Frontiers in Molecular Neuroscience

|June 17, 2026

Summary

This summary is machine-generated.

Researchers developed a new, simple method to visualize brain blood vessels without dyes. This technique aids in studying aging, cerebrovascular diseases, and neurodegenerative disorders.

Keywords:

astrocyte autofluorescence blood vessels blood–brain barrier cerebrovasculature lectin histochemistry microglia neurovascular unit

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Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels

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Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels

Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels

Published on: January 4, 2013

Area of Science:

Neuroscience
Vascular Biology
Medical Imaging

Background:

The brain's vascular system (cerebrovasculature) is vital for neuroscience and medicine.
Cerebrovascular networks change with aging and disease.
Understanding these changes is crucial for diagnosing and treating neurological conditions.

Purpose of the Study:

To introduce a novel, simple method for visualizing cerebrovascular vessels.
To enable multiple labeling with molecular markers for advanced research.
To facilitate research into angiogenesis and remodeling in aging and disease.

Main Methods:

A new visualization technique for cerebrovasculature.
The method does not require exogenous fluorophores (external dyes).
Allows for simultaneous labeling of multiple molecular targets.

Main Results:

Successful visualization of cerebrovascular structures.
Demonstrated simplicity and efficiency of the novel method.
Compatibility with multiple labeling techniques confirmed.

Conclusions:

The developed method offers a straightforward approach to visualize brain vasculature.
It supports advanced research into cerebrovascular changes related to aging and diseases.
This technique is expected to significantly advance studies on angiogenesis, remodeling, and neurodegeneration.